Centerfire rifle cartridges using .224-inch bullets (5.56 mm) – quick access to complete guides, ballistics, and comparison articles.

Cartridges in this catalog:

22 Hornet

22 Hornet is one of the oldest small bore varmint cartridges still in regular use. It is quiet, efficient, and easy on barrels, making it a first choice for close range pest control and small game where noise and meat damage both matter.

222 Remington

222 Remington was the benchmark accuracy cartridge before the 223 arrived. It remains a favorite for benchrest shooters and varmint hunters who want a mild, inherently accurate round with a long barrel life and a well-established reloading tradition.

223 Remington

223 Remington is the civilian counterpart of the 5.56 NATO round and the most widely loaded centerfire rifle cartridge in North America. Component availability is unmatched, and it suits everything from varmint hunting to competition and AR platform shooting.

22 GT

22 GT is a precision wildcatting project built on the 6mm GT case necked down to 22 caliber. It gives high velocity with efficient powder use and excellent BC bullets, attracting handloaders who want a flat-shooting competition and varmint round in a short action platform.

22-250 Remington

22-250 Remington is the traditional long-range varmint standard. It drives light bullets at extremely high velocity from a larger case than the 223, giving a flatter trajectory and more wind resistance for open country coyote and prairie dog shooting at extended ranges.

22 ARC

22 ARC is Hornady’s modern 22-caliber AR platform cartridge. It pushes high-BC .224 bullets at competitive velocities from a short action, with a strong handloading base and growing component support. It covers varmints, competition, and medium game effectively in one package.

22 Creedmoor

22 Creedmoor is the 6.5 Creedmoor case necked down to 22 caliber. It gives substantially more velocity than the 223 while using the same short action platform, and has found a following among long-range varmint hunters and PRS-style competitors who want more reach from a familiar case.

224 Valkyrie

224 Valkyrie was built to push heavy, high-BC .224 bullets to supersonic past 1,300 yards from an AR15 platform. It trades some barrel life for reach, and suits dedicated long-range semi-auto competition and precision varmint work where trajectory and wind drift matter most.

22 Nosler

22 Nosler is Nosler’s AR15-compatible 22-caliber cartridge. It uses a rebated rim to fit a standard bolt face while fitting a larger case body than the 223, giving a meaningful velocity gain for handloaders who want more performance from the AR15 platform without switching bolts.